Doug Altman: A good one gone …

Doug Altman, a professor of statistics at the University of Oxford, died June 3, 2018. Some of his achievements from the Orbituary in The Scientist [1] and Cochrane Library [2]: 1986: Publication of Bland-Altman plot, an incredibly popular technique to visually compare two different methods of taking clinical measurements. According to Nature in 2014, their…

Mirror R/CRAN for internal use

The statistical analysis system R can be extended by a huge number of contributed packages which are stored in the central CRAN repository with multiple synced mirrors around the world. To access this repository from clients in a secure network, and install the packages in a local R installation may pose a security risk, require…

How to calculate (average) hazard ratios for parametric survival models based on the R/flexsurv package

This tutorial [PDF] aims to support the interpretation of parametric time-to-event models by explaining how to calculate the hazard ratio, which is a conventional effect size to evaluate clinical relevance of treatment effects. The following distributions, which are considered most important for health economic analyses, are implemented in the flexsurv package (cf ?flexsurvreg): exp: exponential…

Facial feature representation: The Code for Facial Identity in the Primate Brain

The following paper is a breakthrough in facial feature recognition and numeric representation of facial features and may be helpful to understand the genomic basis of facial features (once the relevant dimensions of the phenome are identified), but also to help to recognize the emotional expression in human faces [1,2]. [1] http://www.cell.com/cell/fulltext/S0092-8674(17)30538-X [2] http://www.bbc.co.uk/news/science-environment-4013124